Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | C5 | P01031 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 3/20 | 0.51 |
| ▸ | PARP1 | P09874 | 3/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229490 | 0.86 | MEN1 (0.51) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL11239778 | 0.83 | PTGS2 (0.57) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL11235661 | 0.83 | KIF11 (0.73) | MEN1MAPTKMT2AKIF11PARP1 | |
| SCHEMBL10888116 | 0.81 | KIF11 (0.66) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL30209160 | 0.80 | KIF11 (0.60) | MEN1MAPTKMT2AKIF11 | |
| SCHEMBL22100411 | 0.80 | KIF11 (0.60) | MEN1MAPTKMT2AKIF11 | |
| SCHEMBL11473567 | 0.80 | PTGS2 (0.51) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL20515867 | 0.80 | MEN1 (0.59) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL675293 | 0.79 | MAP2 (0.40) | MAPTKMT2AKIF11 | |
| SCHEMBL10774096 | 0.78 | PTGS2 (0.54) | PTGS2MEN1ABCC4C5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006606-B1 | PROCESS FOR THE PREPARATION OF CARBAZOLES AND INTERMEDIATES THEREFOR | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-12-29 | — | — | EP | claimed |
| EP-0006606-B1 | PROCESS FOR THE PREPARATION OF CARBAZOLES AND INTERMEDIATES THEREFOR | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-12-29 | — | — | EP | disclosed |