Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | C5 | P01031 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233015 | 0.86 | PTGS2 (0.52) | MEN1MAPTKMT2APTGS2ABCC4 | |
| SCHEMBL11242478 | 0.84 | KDM4E (0.63) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL11475780 | 0.81 | PTGS2 (0.48) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL10774096 | 0.80 | PTGS2 (0.54) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL11239778 | 0.80 | PTGS2 (0.57) | MEN1MAPTKMT2AKDM4EPTGS2 | |
| SCHEMBL10888116 | 0.78 | KIF11 (0.66) | MEN1MAPTKMT2APTGS2ABCC4 | |
| SCHEMBL70604 | 0.77 | ALDH1A1 (0.81) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL20515867 | 0.77 | MEN1 (0.59) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| Methane SCHEMBL28638234 | 0.77 | ALOX15 (0.50) | MEN1MAPTKMT2AALDH1A1PTGS2 | |
| SCHEMBL11398303 | 0.77 | PTGS2 (0.71) | MEN1MAPTKMT2AALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158637-A1 | Synthetic Processes of Carprofen | CHEMWERTH, INC. | 2017-06-08 | — | — | US | disclosed |
| US-20170158637-A1 | Synthetic Processes of Carprofen | CHEMWERTH, INC. | 2017-06-08 | — | — | US | disclosed |
| US-9611217-B2 | Synthetic processes of carprofen | CHEMWERTH, INC. (US) | 2017-04-04 | — | — | US | disclosed |
| US-9611217-B2 | Synthetic processes of carprofen | CHEMWERTH, INC. (US) | 2017-04-04 | — | — | US | disclosed |
| US-20160326113-A1 | Synthetic Processes of Carprofen | CHEMWERTH, INC. | 2016-11-10 | — | — | US | disclosed |
| US-20160326113-A1 | Synthetic Processes of Carprofen | CHEMWERTH, INC. | 2016-11-10 | — | — | US | disclosed |
| EP-3091000-A1 | SYNTHETIC PROCESS OF CARPROFEN | ChemWerth, Inc. (US) | 2016-11-09 | — | — | EP | disclosed |
| EP-0006606-B1 | PROCESS FOR THE PREPARATION OF CARBAZOLES AND INTERMEDIATES THEREFOR | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326113-A1 | Synthetic Processes of Carprofen | CYP4F2, CYP4F3, CYP2J2 | MEN1 4524/4885MAPT 4647/4885KMT2A 3710/4885 |
| US-20170158637-A1 | Synthetic Processes of Carprofen | CYP4F2, CYP4F3, CYP2J2 | MEN1 4524/4885MAPT 4647/4885KMT2A 3710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.