SCHEMBL11233017

SCHEMBL11233017

NCCC(Cc1ccccc1)OC(CCN)Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
EPHX1 P07099 1/20 0.46
HRH1 P35367 1/20 0.45
TAAR1 Q96RJ0 3/20 0.43
SLC6A2 P23975 2/20 0.43
CYP2A6 P11509 2/20 0.43
MAOA P21397 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
LOXL2 Q9Y4K0 2/20 0.43
HTR2A P28223 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ANPEP P15144 1/20 0.41
CYP2D6 P10635 1/20 0.41
SRR Q9GZT4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12569402 0.84 ALDH1A1 (0.53) ALDH1A1EPHX1HRH1TAAR1SLC6A2
SCHEMBL7889486 0.82 EPHX1 (0.52) EPHX1TAAR1SLC6A2CYP2A6MAOA
Ammonia Solution, Strong SCHEMBL15012391 0.80 EPHX1 (0.50) EPHX1TAAR1SLC6A2CYP2A6MAOA
SCHEMBL8750563 0.79 CTSK (0.50) EPHX1TAAR1SLC6A2CYP2A6MAOA
SCHEMBL453958 0.79 TDP1 (0.43) ALDH1A1EPHX1TAAR1SLC6A2CYP2A6
SCHEMBL22122569 0.78 SIGMAR1 (0.47) EPHX1HRH1TAAR1SLC6A2CYP2A6
SCHEMBL4953348 0.78 CTSK (0.51) TAAR1SLC6A2CYP2A6MAOASLC6A4
SCHEMBL2581111 0.76 TDP1 (0.40) ALDH1A1EPHX1TAAR1SLC6A2CYP2A6
SCHEMBL11145503 0.76 EPHX1 (0.52) ALDH1A1EPHX1HRH1TAAR1SLC6A2
SCHEMBL22433619 0.75 IDO1 (0.46) ALDH1A1HRH1TAAR1SLC6A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4352913-A EPOXY RESIN CURING AGENTS CIBA-GEIGY CORPORATION (US) 1982-10-05 US disclosed
US-4324739-A CURING AGENTS FOR POLYEPOXIDES CIBA-GEIGY CORPORATION (US) 1982-04-13 US disclosed