Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520571 | 0.85 | MCL1 (0.71) | ATMRAB9AMCL1L3MBTL1TDP1 | |
| SCHEMBL23532060 | 0.81 | RAB9A (0.60) | ATMRAB9AMCL1L3MBTL1TDP1 | |
| SCHEMBL11095429 | 0.81 | L3MBTL1 (0.61) | ATMRAB9AMCL1L3MBTL1TDP1 | |
| SCHEMBL25706649 | 0.81 | MEN1 (0.57) | ATMRAB9AMCL1L3MBTL1TDP1 | |
| SCHEMBL4745049 | 0.81 | RAB9A (0.56) | RAB9AMCL1L3MBTL1HPGDPTGDR2 | |
| SCHEMBL8486271 | 0.78 | KDM4E (0.53) | RAB9AMCL1L3MBTL1TDP1HPGD | |
| SCHEMBL29958593 | 0.77 | ATM (0.43) | ATMRAB9AL3MBTL1TDP1HPGD | |
| SCHEMBL24110957 | 0.75 | MCL1 (0.56) | ATMRAB9AMCL1L3MBTL1TDP1 | |
| SCHEMBL19024782 | 0.75 | KDM4E (0.64) | ATMRAB9AL3MBTL1TDP1NPSR1 | |
| SCHEMBL22006830 | 0.74 | KDM4E (0.60) | ATMRAB9AL3MBTL1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353923-A | MUSCLE RELAXANTS, ANTIINFLAMMATORY, ANALGESIC | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1982-10-12 | — | — | US | disclosed |
| EP-0045473-A1 | A pharmaceutical composition containing a benzofuran-carboxamide derivative as the active ingredient | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1982-02-10 | — | — | EP | disclosed |