Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.46 |
| ▸ | PTGES | O14684 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123181 | 0.95 | LPAR1 (0.49) | LPAR1PPARGPPARASLC2A1LPAR5 | |
| SCHEMBL1123230 | 0.94 | LPAR1 (0.48) | LPAR1PTGESPPARGPPARATSHR | |
| SCHEMBL1122636 | 0.93 | BCHE (0.50) | PTGESPPARGPPARASLC2A1MEP1B | |
| SCHEMBL1123277 | 0.89 | PPARG (0.49) | LPAR1PTGESPPARGPPARATSHR | |
| SCHEMBL1123052 | 0.88 | NR4A1 (0.45) | LPAR1TSHRHSD17B10SLC2A1KDM4E | |
| SCHEMBL1123244 | 0.85 | LPAR1 (0.52) | LPAR1PTGESPPARGPPARATSHR | |
| SCHEMBL1122912 | 0.84 | LPAR1 (0.49) | LPAR1PTGESPPARGPPARATSHR | |
| SCHEMBL1123189 | 0.84 | LPAR1 (0.51) | LPAR1PPARGPPARASLC2A1LPAR5 | |
| SCHEMBL1123023 | 0.83 | MAOB (0.53) | PTGESSLC2A1KMT2AMAOB | |
| SCHEMBL1122837 | 0.82 | PPARG (0.51) | LPAR1PTGESPPARGPPARATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |