Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123324 | 0.94 | LPAR1 (0.46) | LPAR1LPAR5PPARGPPARASLC2A1 | |
| SCHEMBL1123181 | 0.91 | LPAR1 (0.49) | LPAR1LPAR5PPARGPPARASLC2A1 | |
| SCHEMBL1122837 | 0.88 | PPARG (0.51) | LPAR1LPAR5PPARGPPARASLC2A1 | |
| SCHEMBL1122799 | 0.87 | L3MBTL1 (0.53) | LPAR1LPAR5LTA4HNPC1LMNA | |
| SCHEMBL1122636 | 0.86 | BCHE (0.50) | PPARGPPARASLC2A1PTGESNPC1 | |
| SCHEMBL1122692 | 0.85 | LPAR1 (0.55) | LPAR1LPAR5PPARGPPARASLC2A1 | |
| SCHEMBL1123335 | 0.84 | LPAR1 (0.52) | LPAR1LPAR5PPARGPPARASLC2A1 | |
| SCHEMBL1123277 | 0.82 | PPARG (0.49) | LPAR1LPAR5PPARGPPARASLC2A1 | |
| SCHEMBL1123229 | 0.81 | SLC2A1 (0.55) | SLC2A1PTGESNPC1LMNAALOX5 | |
| SCHEMBL1123052 | 0.81 | NR4A1 (0.45) | LPAR1SLC2A1LTA4HTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |