Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.49 |
| ▸ | PTGES | O14684 | 3/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123244 | 0.93 | LPAR1 (0.52) | LPAR1PTGESLPAR5F10PPARG | |
| SCHEMBL1123335 | 0.93 | LPAR1 (0.52) | LPAR1PTGESLPAR5PPARGKDM4E | |
| SCHEMBL1123557 | 0.92 | PTGES (0.52) | PTGESF10PPARGKMT2ASLC2A1 | |
| SCHEMBL1123277 | 0.91 | PPARG (0.49) | LPAR1PTGESLPAR5F10PPARG | |
| SCHEMBL1122385 | 0.89 | PPARG (0.47) | LPAR1F10PPARGKDM4EKMT2A | |
| SCHEMBL1123395 | 0.89 | F10 (0.51) | LPAR1PTGESF10PPARGKMT2A | |
| SCHEMBL1123247 | 0.88 | SLC2A1 (0.47) | LPAR1F10PPARGKMT2ASLC2A1 | |
| SCHEMBL1123394 | 0.87 | KMT2A (0.52) | PTGESF10PPARGKMT2AL3MBTL1 | |
| SCHEMBL1122952 | 0.86 | LPAR1 (0.53) | LPAR1LPAR5FFAR1 | |
| SCHEMBL1122692 | 0.86 | LPAR1 (0.55) | LPAR1PTGESLPAR5PPARGSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| US-20060160894-A1 | Benzamides as ppar modulators | LABORATORIOS S.A.L.V.A.T.,S.A. (ES) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | PPARD, PPARA, PPARG | LPAR1 608/4885PTGES 110/4885LPAR5 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.