SCHEMBL11233468

SCHEMBL11233468

CNC(=O)N(C)C(=O)Oc1c(C(C)(C)C)cc(C)cc1C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
CA2 P00918 1/20 0.37
POLB P06746 1/20 0.37
TYR P14679 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8536538 0.78 ALDH1A1 (0.44) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL132875 0.78 ALDH1A1 (0.44) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL8094382 0.73 ALDH1A1 (0.45) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL6912228 0.73 VCAM1 (0.49) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL8407409 0.72 ALDH1A1 (0.48) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL11211097 0.69 ACHE (0.42)
SCHEMBL17171717 0.68 ALDH1A1 (0.44) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL14977109 0.68 VCAM1 (0.64)
SCHEMBL26078833 0.67 ALDH1A1 (0.42) ALDH1A1CA2POLBTYRSMN1; SMN2
SCHEMBL16965795 0.67 NCEH1 (0.41) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4354979-A Preparation of aliphatic isocyanates BASF AKTIENGESELLSCHAFT (DE) 1982-10-19 US disclosed