SCHEMBL1123354

SCHEMBL1123354

C=C(C)C(=O)NCCOCCC

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 5/20 0.44
THRB P10828 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ACHE P22303 1/20 0.38
TSHR P16473 2/20 0.36
ALDH1A1 P00352 2/20 0.36
NAMPT P43490 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4854125 0.98 THRB (0.44) EPHX2THRBMEN1KMT2AACHE
SCHEMBL12036308 0.92 MEN1 (0.47) EPHX2THRBMEN1KMT2AACHE
SCHEMBL4846049 0.91 ACHE (0.43) EPHX2THRBACHETSHRALDH1A1
SCHEMBL13862904 0.90 MEN1 (0.50) EPHX2THRBMEN1KMT2AACHE
SCHEMBL18016179 0.90 MEN1 (0.50) EPHX2THRBMEN1KMT2AACHE
SCHEMBL26085057 0.89 ACHE (0.42) EPHX2THRBMEN1KMT2AACHE
SCHEMBL554259 0.89 ACHE (0.44) EPHX2THRBMEN1KMT2AACHE
SCHEMBL24715032 0.88 EPHX2 (0.45) EPHX2THRBACHETSHR
SCHEMBL2534633 0.87 ACHE (0.43) EPHX2THRBMEN1KMT2AACHE
SCHEMBL555013 0.87 ACHE (0.43) EPHX2THRBMEN1KMT2AACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2000505-B1 HIGH-STRENGTH ADHESIVE POLYMER GEL AND ADHESIVE TAPE SEKISUI PLASTICS (JP) 2011-02-09 EP claimed
US-7329694-B2 Ocular lens JOHNSON & JOHNSON VISION CARE, INC. (US) 2008-02-12 US claimed
US-10377903-B2 Nanoparticle-containing solution and use thereof SEKISUI PLASTICS CO., LTD. (JP) 2019-08-13 US disclosed
EP-3106495-B1 NANOPARTICLE-CONTAINING SOLUTION AND USE THEREOF SEKISUI PLASTICS (JP) 2018-10-17 EP disclosed
US-20170101538-A1 NANOPARTICLE-CONTAINING SOLUTION AND USE THEREOF SEKISUI PLASTICS CO., LTD. (JP) 2017-04-13 US disclosed
EP-3106495-A1 NANOPARTICLE-CONTAINING SOLUTION AND USE THEREOF Sekisui Plastics Co., Ltd. (JP) 2016-12-21 EP disclosed
EP-2000505-B1 HIGH-STRENGTH ADHESIVE POLYMER GEL AND ADHESIVE TAPE SEKISUI PLASTICS (JP) 2011-02-09 EP disclosed
US-7329694-B2 Ocular lens JOHNSON & JOHNSON VISION CARE, INC. (US) 2008-02-12 US disclosed
US-7208012-B2 Covalently-bound, hydrophilic coating compositions for surgical implants ALCON, INC. (CH) 2007-04-24 US disclosed
US-20070043436-A1 COVALENTLY-BOUND, HYDROPHILIC COATING COMPOSITIONS FOR SURGICAL IMPLANTS ALCON, INC. (CH) 2007-02-22 US disclosed
US-7157538-B2 Covalently-bound, hydrophilic coating compositions for surgical implants ALCON, INC. (CH) 2007-01-02 US disclosed
US-20040201820-A1 Ocular lens JOHNSON & JOHNSON VISION CARE, INC. 2004-10-14 US disclosed
EP-1445641-A1 OCULAR LENS Johnson & Johnson Vision Care, Inc. (US) 2004-08-11 EP disclosed