Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26085057 | 0.98 | ACHE (0.42) | ACHEMMP9MMP8MMP14SMN1; SMN2 | |
| SCHEMBL24715032 | 0.93 | EPHX2 (0.45) | ACHEEPHX2TSHRTHRB | |
| SCHEMBL4853585 | 0.93 | SMN1; SMN2 (0.48) | ACHEMMP9MMP8MMP14SMN1; SMN2 | |
| SCHEMBL24496157 | 0.93 | ALDH1A1 (0.41) | ACHEMMP9MMP8MMP14SMN1; SMN2 | |
| SCHEMBL5528349 | 0.91 | THRB (0.41) | ACHEMMP9MMP8MMP14SMN1; SMN2 | |
| SCHEMBL1123354 | 0.91 | EPHX2 (0.44) | ACHESMN1; SMN2EPHX2TSHRTHRB | |
| SCHEMBL8949910 | 0.91 | THRB (0.41) | ACHEMMP9MMP8MMP14SMN1; SMN2 | |
| SCHEMBL5413785 | 0.91 | ALDH1A1 (0.40) | ACHEMMP9MMP8MMP14SMN1; SMN2 | |
| SCHEMBL4854125 | 0.89 | THRB (0.44) | ACHESMN1; SMN2EPHX2TSHRTHRB | |
| SCHEMBL13862877 | 0.89 | CYP2C19 (0.41) | ACHEMMP9MMP8MMP14SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329694-B2 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-02-12 | — | — | US | claimed |
| US-7329694-B2 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-02-12 | — | — | US | disclosed |
| US-7208139-B2 | Conducting nuclear spin tomography on a patient who has been administered a cascade polymer complex having complex-forming ligands for imaging of inflammation and/or tumors in the brain | SCHERING AG (DE) | 2007-04-24 | — | — | US | disclosed |
| US-20040201820-A1 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. | 2004-10-14 | — | — | US | disclosed |
| EP-1445641-A1 | OCULAR LENS | Johnson & Johnson Vision Care, Inc. (US) | 2004-08-11 | — | — | EP | disclosed |