SCHEMBL11233663

SCHEMBL11233663

CCCCCC(C)(C)c1ccc(OS(=O)(=O)c2ccccc2)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 8/20 0.39
CNR2 P34972 8/20 0.39
KDM4E B2RXH2 4/20 0.38
NPC1 O15118 6/20 0.36
RAB9A P51151 6/20 0.36
SMN1; SMN2 Q16637 5/20 0.36
MAPT P10636 3/20 0.35
ALDH1A1 P00352 4/20 0.35
HPGD P15428 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
HSD11B1 P28845 1/20 0.34
HSD17B3 P37058 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11236765 0.93 KDM4E (0.43) CNR1CNR2KDM4ENPC1RAB9A
SCHEMBL11237186 0.92 CNR2 (0.40) CNR1CNR2KDM4ESMN1; SMN2TDP1
SCHEMBL11233656 0.86 KDM4E (0.39) KDM4ENPC1RAB9ASMN1; SMN2MAPT
SCHEMBL6103630 0.81 CNR1 (0.32) CNR1CNR2
SCHEMBL11236764 0.80 KDM4E (0.45) KDM4ENPC1RAB9ASMN1; SMN2MAPT
SCHEMBL11244033 0.80 KDM4E (0.42) KDM4ENPC1RAB9ASMN1; SMN2MAPT
SCHEMBL7186178 0.78 KDM4E (0.40) CNR1CNR2KDM4ENPC1RAB9A
SCHEMBL11237184 0.78 HTT (0.40) KDM4ENPC1RAB9ASMN1; SMN2MAPT
SCHEMBL4649274 0.78 NPC1 (0.47) CNR1CNR2KDM4ENPC1RAB9A
SCHEMBL11542390 0.78 ALDH1A1 (0.42) CNR1CNR2KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4344830-A WEATHERPROOFING GENERAL ELECTRIC COMPANY (US) 1982-08-17 US disclosed