Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235371 | 0.89 | ALDH1A1 (0.47) | HPGDTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL11233109 | 0.84 | HSD17B2 (0.48) | HPGDTDP1TP53PARP1 | |
| SCHEMBL18773872 | 0.79 | HPGD (0.64) | HPGDTDP1HDAC8MEN1KMT2A | |
| Water SCHEMBL11233729 | 0.77 | HPGD (0.57) | HPGDTDP1HDAC8MEN1KMT2A | |
| Water SCHEMBL11233763 | 0.77 | HPGD (0.57) | HPGDTDP1HDAC8MEN1KMT2A | |
| SCHEMBL11251117 | 0.74 | SENP1 (0.48) | TSHRALDH1A1TP53LMNAMAPT | |
| SCHEMBL11227688 | 0.72 | SMN1; SMN2 (0.52) | TSHRALDH1A1HTTTP53LMNA | |
| SCHEMBL11230427 | 0.72 | GFER (0.43) | HPGDKMT2ATSHRALDH1A1HTT | |
| SCHEMBL3456171 | 0.71 | TSHR (0.75) | HPGDTDP1MEN1KMT2ATSHR | |
| SCHEMBL11238514 | 0.70 | MLYCD (0.34) | TDP1MEN1KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361579-A | TREATMENT OF IMMUNE DISEASES WITH ORGANOGERMANIUM POLYMERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1982-11-30 | — | — | US | disclosed |
| EP-0025965-A2 | Organogermanium compounds, a method for producing them and pharmaceutical compositions comprising them | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1981-04-01 | — | — | EP | disclosed |