Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19202196 | 0.86 | TRPM4 (0.50) | TRPM4AHRNQO2NCEH1CYP1A2 | |
| SCHEMBL8090751 | 0.86 | TRPM4 (0.50) | TRPM4AHRNQO2CYP1A2ALOX5 | |
| SCHEMBL27051333 | 0.85 | TRPM4 (0.48) | TRPM4AHRNQO2NCEH1CYP1A2 | |
| SCHEMBL23979723 | 0.83 | TRPM4 (0.47) | TRPM4AHRNQO2NCEH1CYP1A2 | |
| SCHEMBL27051382 | 0.83 | TRPM4 (0.47) | TRPM4AHRNQO2NCEH1CYP1A2 | |
| SCHEMBL40806 | 0.81 | ALDH1A1 (0.44) | TRPM4AHRNQO2NCEH1CYP1A2 | |
| SCHEMBL5843636 | 0.79 | ERN1 (0.53) | TRPM4AHRNQO2CYP1A2MEN1 | |
| SCHEMBL682421 | 0.78 | KMT2A (0.55) | NCEH1CYP1A2MEN1KMT2AGAA | |
| SCHEMBL72911 | 0.78 | SIGMAR1 (0.39) | TRPM4NCEH1CYP1A2GABRA1GABRB2 | |
| SCHEMBL6546711 | 0.78 | CYP1A2 (0.47) | NCEH1CYP1A2GAAMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323714-A | Alkylation of hydroxy-substituted aromatic compounds | UOP INC. (US) | 1982-04-06 | — | — | US | disclosed |