Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.50 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233768 | 0.86 | TRPM4 (0.52) | TRPM4PTPN22AHRNQO2GABRA1 | |
| SCHEMBL19202196 | 0.85 | TRPM4 (0.50) | TRPM4PTPN22AHRNQO2GABRA1 | |
| SCHEMBL6909795 | 0.83 | GABRA1 (0.42) | TRPM4PTPN22NQO2GABRA1GABRB2 | |
| SCHEMBL27051333 | 0.79 | TRPM4 (0.48) | TRPM4PTPN22AHRNQO2GABRA1 | |
| SCHEMBL23979723 | 0.78 | TRPM4 (0.47) | TRPM4PTPN22AHRNQO2GABRA1 | |
| SCHEMBL9862272 | 0.78 | RNASEH1 (0.44) | AHRGABRA1GABRB2CASP6NQO1 | |
| SCHEMBL27051382 | 0.78 | TRPM4 (0.47) | TRPM4PTPN22AHRNQO2GABRA1 | |
| SCHEMBL5843636 | 0.78 | ERN1 (0.53) | TRPM4AHRNQO2CYP1A2LMNA | |
| SCHEMBL21962162 | 0.76 | GABRA1 (0.42) | TRPM4NQO2GABRA1GABRB2CYP1A2 | |
| Ethane SCHEMBL28303517 | 0.75 | TRPM4 (0.58) | TRPM4PTPN22NQO2CASP6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107527-A | BY MEANS OF CATALYTIC OXIDATION OF ISOALKYL AROMATIC SUBSTANCE WITH OXYGEN, AND DECOMPOSITION OF THE HYDROPEROXIDE THUS FORMED | RUTGERS KUREHA SOLVENTS GMBH (DE) | 2000-08-22 | — | — | US | disclosed |