Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249765 | 0.78 | ADORA3 (0.37) | ADORA3TSHRPPARGPPARACYP1A2 | |
| SCHEMBL7351412 | 0.78 | ADORA3 (0.37) | ADORA3TSHRPPARGPPARACYP1A2 | |
| SCHEMBL16077366 | 0.77 | RARB (0.36) | ADORA3TSHRMAPK1 | |
| SCHEMBL31666359 | 0.77 | TSHR (0.33) | TSHR | |
| SCHEMBL11062288 | 0.76 | MAPK1 (0.36) | TSHRMAPK1SLC16A3SLC16A1PPARG | |
| SCHEMBL27730942 | 0.74 | PPARA (0.36) | ADORA3TSHRSLC16A3SLC16A1PPARG | |
| SCHEMBL11246102 | 0.71 | MMP8 (0.44) | MMP8 | |
| SCHEMBL3284625 | 0.71 | ALDH1A1 (0.40) | ADORA3TSHRMAPK1PPARGPPARA | |
| SCHEMBL28774470 | 0.71 | TSHR (0.33) | TSHR | |
| SCHEMBL7200959 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347379-A | REACTING AN ALCOHOL OF THIOL, A HALOFORM, ALKALI METAL HYDROXIDE, AND PHASE TRANSFER AGENT | THE B. F. GOODRICH COMPANY (US) | 1982-08-31 | — | — | US | disclosed |