Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11230529 | 0.89 | MAPT (0.50) | MAPTMEN1KMT2AHTTADRB1 | |
| SCHEMBL11237785 | 0.87 | SCN4A (0.46) | MAPTMEN1KMT2AHTTGAA | |
| SCHEMBL11240121 | 0.86 | CASR (0.48) | MAPTMEN1KMT2AHTTHPGD | |
| SCHEMBL11230723 | 0.82 | MEN1 (0.48) | MAPTMEN1KMT2AHTTHPGD | |
| SCHEMBL11237823 | 0.81 | MAPT (0.42) | MAPTMEN1KMT2AHTTGAA | |
| SCHEMBL11234636 | 0.80 | HTT (0.41) | MAPTMEN1KMT2AHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL11236940 | 0.80 | MAPT (0.41) | MAPTMEN1KMT2AHTTGAA | |
| SCHEMBL11238954 | 0.79 | MAPT (0.47) | MAPTHTTHPGDMAPK1ADRB1 | |
| Hydrochloric Acid SCHEMBL11235230 | 0.78 | MAPT (0.46) | MAPTHTTHPGDMAPK1ADRB1 | |
| SCHEMBL11243705 | 0.77 | TSHR (0.46) | MAPTMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | disclosed |