Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11236940 | 0.99 | MAPT (0.41) | MAPTHTTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL11234636 | 0.89 | HTT (0.41) | MAPTHTTSMN1; SMN2LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL11230529 | 0.88 | MAPT (0.50) | MAPTHTTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL11238954 | 0.88 | MAPT (0.47) | MAPTHTTSMN1; SMN2LMNAADRB1 | |
| Hydrochloric Acid SCHEMBL11235230 | 0.87 | MAPT (0.46) | MAPTHTTSMN1; SMN2LMNAADRB1 | |
| SCHEMBL11246090 | 0.84 | MAPT (0.50) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL11230236 | 0.83 | ALDH1A1 (0.50) | MAPTSMN1; SMN2MEN1KMT2AADRB1 | |
| Hydrochloric Acid SCHEMBL11247363 | 0.82 | ADRB1 (0.50) | MAPTSMN1; SMN2MEN1KMT2AADRB1 | |
| SCHEMBL11233872 | 0.81 | MAPT (0.45) | MAPTHTTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL11237785 | 0.81 | SCN4A (0.46) | MAPTHTTSMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |