Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230236 | 0.88 | ALDH1A1 (0.50) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL11247363 | 0.87 | ADRB1 (0.50) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL11230529 | 0.84 | MAPT (0.50) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL11233872 | 0.82 | MAPT (0.45) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL11237785 | 0.82 | SCN4A (0.46) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL11241745 | 0.82 | MAPT (0.60) | KMT2AADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL11240121 | 0.81 | CASR (0.48) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL11230720 | 0.78 | ADRB1 (0.67) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL11230725 | 0.78 | MAPT (0.48) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL11237823 | 0.76 | MAPT (0.42) | MEN1KMT2AADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | disclosed |