Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 6/20 | 0.64 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | GUSB | P08236 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27658958 | 1.00 | GPR132 (0.64) | GPR132SMPD1MAOBNR4A2MEN1 | |
| SCHEMBL1123498 | 0.94 | GPR132 (0.63) | GPR132SMPD1MAOBNR4A2MEN1 | |
| SCHEMBL1123133 | 0.91 | GPR132 (0.77) | GPR132SMPD1MAOBNR4A2MEN1 | |
| SCHEMBL1123158 | 0.85 | GPR132 (0.77) | GPR132SMPD1MAOBNR4A2ALDH1A1 | |
| SCHEMBL1123022 | 0.85 | GPR132 (0.75) | GPR132SMPD1MAOBNR4A2NR1H4 | |
| SCHEMBL13702183 | 0.83 | GPR132 (0.73) | GPR132SMPD1MAOBNR4A2MEN1 | |
| SCHEMBL4893620 | 0.83 | GPR132 (0.69) | GPR132SMPD1MAOBNR4A2MEN1 | |
| SCHEMBL8303424 | 0.80 | GPR132 (0.69) | GPR132SMPD1MAOBNR4A2MEN1 | |
| SCHEMBL16767403 | 0.80 | PPARG (0.66) | MAOBMEN1KMT2A | |
| SCHEMBL8303422 | 0.80 | GPR132 (0.69) | GPR132SMPD1MAOBNR4A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| EP-1644321-A2 | NEW BENZAMIDES AS PPATY MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110983-A2 | NEW BENZAMIDES AS PPARϒ MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-12-23 | — | — | WO | disclosed |