Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNG | P07510 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242731 | 0.93 | L3MBTL1 (0.34) | L3MBTL1ICMTLMNAALDH1A1CYP3A4 | |
| SCHEMBL11244126 | 0.89 | L3MBTL1 (0.31) | L3MBTL1 | |
| SCHEMBL11234430 | 0.84 | SLC6A3 (0.37) | ICMTALDH1A1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL4613107 | 0.83 | L3MBTL1 (0.33) | L3MBTL1LMNACHRNA1CHRNGCHRNB1 | |
| SCHEMBL11252318 | 0.82 | MAPK1 (0.40) | L3MBTL1ICMTHTR1ATSHR | |
| SCHEMBL11239617 | 0.82 | SLC6A4 (0.37) | ICMTALDH1A1CYP3A4CYP2C19OPRM1 | |
| SCHEMBL11237330 | 0.82 | KCNH2 (0.41) | ICMTALDH1A1HTTTSHRKMT2A | |
| SCHEMBL11241229 | 0.81 | CHRNA1 (0.36) | L3MBTL1ICMTLMNAALDH1A1CYP3A4 | |
| SCHEMBL11241311 | 0.81 | L3MBTL1 (0.32) | L3MBTL1LMNACHRNA1CHRNGCHRNB1 | |
| SCHEMBL11243674 | 0.80 | MAOB (0.33) | L3MBTL1LMNAMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |