Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ICMT | O60725 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNG | P07510 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRND | Q07001 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250459 | 0.94 | SMN1; SMN2 (0.38) | SLC6A4SLC6A3SMN1; SMN2ICMTMAOB | |
| SCHEMBL11239210 | 0.90 | RYR2 (0.35) | SLC6A4SLC6A3SMN1; SMN2ICMTMAOB | |
| SCHEMBL1593292 | 0.84 | SMN1; SMN2 (0.36) | SMN1; SMN2ICMTMAOBMAOAGRIN1 | |
| SCHEMBL11246464 | 0.83 | GRIN1 (0.40) | SLC6A4SLC6A3SMN1; SMN2ICMTMAOB | |
| SCHEMBL11237020 | 0.83 | RYR2 (0.36) | SMN1; SMN2ICMTMAOBMAOAGRIN1 | |
| SCHEMBL11249163 | 0.82 | TSHR (0.44) | CYP2C19ALDH1A1CA12CA1CA2 | |
| SCHEMBL11234170 | 0.82 | L3MBTL1 (0.33) | SLC6A3ICMTMAOBMAOACYP3A4 | |
| SCHEMBL11247712 | 0.82 | MAOB (0.37) | SLC6A4SLC6A3ICMTMAOBMAOA | |
| SCHEMBL9517524 | 0.81 | MAOB (0.41) | SLC6A4SLC6A3SMN1; SMN2MAOBMAOA | |
| SCHEMBL11234430 | 0.80 | SLC6A3 (0.37) | SLC6A4SLC6A3ICMTMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |