SCHEMBL11234409

SCHEMBL11234409

CC(C)N1CC(OCc2ccc(Cl)cc2)C1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 2/20 0.48
PRMT6 Q96LA8 2/20 0.48
SLC6A4 P31645 1/20 0.42
NAAA Q02083 6/20 0.41
TACR1 P25103 1/20 0.41
CTSL P07711 1/20 0.40
CTSB P07858 1/20 0.40
CTSK P43235 1/20 0.40
IDO1 P14902 2/20 0.39
AGXT P21549 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11231901 0.87 NAAA (0.43) CARM1PRMT6NAAACTSLCTSB
SCHEMBL11236472 0.85 NAAA (0.56) CARM1PRMT6NAAATACR1CTSL
SCHEMBL11221320 0.83 CTSL (0.57) CARM1PRMT6SLC6A4NAAATACR1
SCHEMBL11234577 0.83 NAAA (0.58) SLC6A4NAAATACR1IDO1AGXT
SCHEMBL11223806 0.81 CARM1 (0.55) CARM1PRMT6SLC6A4NAAACTSL
SCHEMBL11227595 0.80 NAAA (0.43) CARM1PRMT6NAAACTSLCTSB
SCHEMBL4635795 0.79 TACR1 (0.49) SLC6A4NAAATACR1CTSLCTSB
SCHEMBL11232037 0.79 CARM1 (0.52) CARM1PRMT6SLC6A4NAAACTSL
SCHEMBL11232833 0.77 CARM1 (0.48) CARM1PRMT6SLC6A4NAAATACR1
SCHEMBL20068825 0.75 HRH3 (0.46) SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4360464-A Process for production of 1-aryloxy-aminopropane derivatives TEIKOKU HORMONE MFG. CO. LTD. (JP) 1982-11-23 US claimed
US-4360464-A Process for production of 1-aryloxy-aminopropane derivatives TEIKOKU HORMONE MFG. CO. LTD. (JP) 1982-11-23 US disclosed
US-4018824-A ANTIULCER AND ADRENERGIC BLOCKING AGENTS TEIKOKU HORMONE MFG. CO., LTD. (JA) 1977-04-19 US disclosed