Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 5/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11231901 | 0.86 | NAAA (0.43) | NAAAHRH3POLBCTSLCTSB | |
| SCHEMBL11234577 | 0.85 | NAAA (0.58) | NAAAALDH1A1MEN1KMT2AHRH3 | |
| SCHEMBL11225338 | 0.84 | NAAA (0.47) | NAAANQO1ALDH1A1MAPTMEN1 | |
| SCHEMBL11230944 | 0.82 | NAAA (0.45) | NAAANQO1ALDH1A1MAPTMEN1 | |
| SCHEMBL11236472 | 0.81 | NAAA (0.56) | NAAACTSLCTSBCTSKCARM1 | |
| SCHEMBL11234409 | 0.80 | CARM1 (0.48) | NAAACTSLCTSBCTSKCARM1 | |
| SCHEMBL11221320 | 0.80 | CTSL (0.57) | NAAAHRH3CTSLCTSBCTSK | |
| SCHEMBL11232830 | 0.79 | NAAA (0.43) | NAAANQO1ALDH1A1MAPTMEN1 | |
| SCHEMBL11233979 | 0.74 | TP53 (0.52) | NAAAACACBALDH1A1MAPTMEN1 | |
| SCHEMBL11226439 | 0.73 | NAAA (0.45) | NAAAHRH3CTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | claimed |
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | disclosed |
| US-4018824-A | ANTIULCER AND ADRENERGIC BLOCKING AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |