Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.61 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283740 | 0.89 | FFAR4 (0.58) | FFAR4PPARAPPARGESR1ESR2 | |
| SCHEMBL11243631 | 0.86 | FFAR4 (0.46) | FFAR4PPARAPPARGESR1ESR2 | |
| SCHEMBL11251381 | 0.78 | FFAR4 (0.77) | FFAR4PPARGESR1ESR2SMN1; SMN2 | |
| SCHEMBL10657410 | 0.77 | MAPT (0.41) | PPARAPPARGSMN1; SMN2TP53MAPT | |
| SCHEMBL10659324 | 0.77 | PPARA (0.52) | FFAR4PPARAPPARGSMN1; SMN2LMNA | |
| SCHEMBL10658961 | 0.77 | PPARA (0.48) | PPARAPPARG | |
| SCHEMBL10665132 | 0.77 | PPARA (0.40) | FFAR4PPARAPPARGSMN1; SMN2NPSR1 | |
| SCHEMBL11244680 | 0.76 | FFAR4 (0.64) | FFAR4ESR1ESR2SMN1; SMN2TP53 | |
| SCHEMBL11247085 | 0.76 | FFAR4 (0.45) | FFAR4PPARAPPARGESR1ESR2 | |
| SCHEMBL10661841 | 0.76 | MAPT (0.41) | FFAR4PPARAPPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337261-A | (1,2-Benzisoxazol)phenoxyacetic acids as diuretics | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-06-29 | — | — | US | disclosed |
| EP-0045078-A1 | (1,2-Benzisoxazol)phenoxyacetic acids and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1982-02-03 | — | — | EP | disclosed |