Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247085 | 0.89 | FFAR4 (0.45) | FFAR4PPARAPPARGESR1ESR2 | |
| SCHEMBL11234752 | 0.86 | FFAR4 (0.61) | FFAR4PPARAPPARGESR1ESR2 | |
| SCHEMBL11243606 | 0.79 | FFAR4 (0.55) | FFAR4PPARAPPARGESR1ESR2 | |
| SCHEMBL11247022 | 0.76 | ALDH1A1 (0.47) | FFAR4ESR1ESR2PTPN1NPSR1 | |
| SCHEMBL11283740 | 0.75 | FFAR4 (0.58) | FFAR4PPARAPPARGESR1ESR2 | |
| SCHEMBL11257225 | 0.72 | FFAR4 (0.63) | FFAR4PPARGESR1ESR2PTPN1 | |
| SCHEMBL10658761 | 0.72 | PPARA (0.39) | PPARAPPARGSMN1; SMN2PPARDPTGDR2 | |
| SCHEMBL10665132 | 0.71 | PPARA (0.40) | FFAR4PPARAPPARGNPSR1SMN1; SMN2 | |
| SCHEMBL11255027 | 0.70 | FFAR4 (0.63) | FFAR4ESR1ESR2PTPN1SMN1; SMN2 | |
| SCHEMBL10657410 | 0.70 | MAPT (0.41) | PPARAPPARGSMN1; SMN2PPARDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337261-A | (1,2-Benzisoxazol)phenoxyacetic acids as diuretics | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1982-06-29 | — | — | US | disclosed |
| EP-0045078-A1 | (1,2-Benzisoxazol)phenoxyacetic acids and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1982-02-03 | — | — | EP | disclosed |