Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16805860 | 0.84 | TSHR (0.54) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL17522059 | 0.82 | TSHR (0.52) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL29060324 | 0.80 | TSHR (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL28330305 | 0.80 | TSHR (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL7776385 | 0.80 | ALDH1A1 (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL23281614 | 0.78 | TSHR (0.48) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL844941 | 0.78 | TSHR (0.59) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL15889487 | 0.78 | ALDH1A1 (0.43) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL7768846 | 0.77 | TSHR (0.52) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL10626929 | 0.76 | TSHR (0.56) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366099-A | HEATING WITH HOMOPOLYMERIZABLE, HYDROPHILIC MONOMER; FREE RADICAL CATALYST | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-12-28 | — | — | US | claimed |