Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | STAT6 | P42226 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111718 | 0.84 | TSHR (0.60) | LMNAMAPTPOLBPKMESR1 | |
| SCHEMBL30943786 | 0.82 | LMNA (0.50) | LMNAMAPTPOLBPKMESR1 | |
| SCHEMBL24171452 | 0.81 | LMNA (0.48) | LMNAMAPTPOLBPKMESR1 | |
| SCHEMBL13784555 | 0.81 | LMNA (0.48) | LMNAMAPTPOLBPKMESR1 | |
| SCHEMBL19968620 | 0.81 | ESR1 (0.55) | LMNAMAPTPOLBPKMESR1 | |
| SCHEMBL8476326 | 0.81 | FFAR1 (0.53) | LMNAMAPTPOLBPKMESR1 | |
| SCHEMBL6931924 | 0.80 | LMNA (0.44) | LMNAMAPTPOLBPKMESR1 | |
| SCHEMBL13799154 | 0.79 | TAAR1 (0.49) | LMNAMAPTPOLBPKMESR1 | |
| SCHEMBL23502928 | 0.79 | LMNA (0.47) | LMNAMAPTPOLBPKMESR1 | |
| SCHEMBL1714626 | 0.79 | LMNA (0.59) | LMNAMAPTPOLBPKMESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328361-A | Novel process | THE UPJOHN COMPANY (US) | 1982-05-04 | — | — | US | disclosed |