Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.57 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2031092 | 0.82 | KCNK2 (0.64) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL13802483 | 0.82 | WDR5 (0.60) | SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL11239532 | 0.81 | ABCB1 (0.57) | ALDH1A1ABCB1ABCC1SMN1; SMN2MEN1 | |
| SCHEMBL11228267 | 0.81 | MEN1 (0.69) | ALDH1A1SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL9352575 | 0.80 | AKR1C3 (0.56) | SMN1; SMN2MEN1KMT2AKCNMA1L3MBTL1 | |
| SCHEMBL13802484 | 0.79 | HTT (0.74) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4699872 | 0.79 | CHEK1 (0.76) | ALDH1A1ABCB1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2024935 | 0.79 | MEN1 (0.71) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL11573780 | 0.79 | AKR1C4 (0.64) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL13561219 | 0.77 | MEN1 (0.76) | ALDH1A1SMN1; SMN2MEN1KMT2AKCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337270-A | ANTIALLERGENS; ANTIANAPHYLACTIC AGENTS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1982-06-29 | — | — | US | disclosed |