Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | YAP1 | P46937 | 2/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | IL1RN | P18510 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123515 | 1.00 | GAA (0.55) | GAARAB9AERAP2LNPEPPPARG | |
| SCHEMBL1123251 | 0.93 | PTPN1 (0.56) | PPARGPTPN1GPR132 | |
| SCHEMBL1122872 | 0.84 | GAA (0.58) | GAARAB9AERAP2LNPEPPPARG | |
| SCHEMBL1123055 | 0.82 | GAA (0.80) | GAARAB9AERAP2LNPEPPPARG | |
| SCHEMBL1122711 | 0.81 | GAA (0.59) | GAARAB9AERAP2LNPEPPPARG | |
| SCHEMBL1123382 | 0.80 | GAA (0.71) | GAARAB9AERAP2LNPEPPPARG | |
| SCHEMBL1123147 | 0.80 | GAA (0.71) | GAARAB9AERAP2LNPEPPPARG | |
| SCHEMBL27638047 | 0.80 | RAB9A (0.74) | GAARAB9AERAP2LNPEPPPARG | |
| SCHEMBL1122610 | 0.80 | RAB9A (0.74) | GAARAB9AERAP2LNPEPPPARG | |
| SCHEMBL1122832 | 0.80 | GAA (0.62) | GAARAB9AERAP2LNPEPPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |