Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.51 |
| ▸ | SHBG | P04278 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.51 |
| ▸ | PGR | P06401 | 3/20 | 0.51 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | AR | P10275 | 3/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SNCA | P37840 | 2/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.46 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235253 | 1.00 | CYP19A1 (0.51) | CYP19A1SHBGHSD17B10NR3C1PGR | |
| SCHEMBL11239863 | 0.86 | SRD5A1 (0.43) | ARGPBAR1SRD5A1SRD5A2 | |
| SCHEMBL11239844 | 0.86 | SRD5A1 (0.43) | ARGPBAR1SRD5A1SRD5A2 | |
| SCHEMBL11257889 | 0.85 | HSD17B3 (0.53) | CYP19A1SHBGSERPINA6CYP3A4GPBAR1 | |
| SCHEMBL11257890 | 0.85 | HSD17B3 (0.53) | CYP19A1SHBGSERPINA6CYP3A4GPBAR1 | |
| SCHEMBL28290732 | 0.83 | CYP19A1 (0.60) | CYP19A1SHBGHSD17B10NR3C1PGR | |
| SCHEMBL11242975 | 0.82 | CYP17A1 (0.50) | GPBAR1SRD5A1SRD5A2 | |
| SCHEMBL11243498 | 0.82 | SRD5A2 (0.59) | HSD17B10GPBAR1LMNAKMT2ASRD5A1 | |
| SCHEMBL11242981 | 0.82 | CYP17A1 (0.50) | GPBAR1SRD5A1SRD5A2 | |
| SCHEMBL11243490 | 0.82 | SRD5A2 (0.59) | HSD17B10GPBAR1LMNAKMT2ASRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317817-A | SKIN DISORDERS; ACEME; ENZYME INHIBITORS | RICHARDSON-MERRELL INC. (US) | 1982-03-02 | — | — | US | disclosed |