Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | EBP | Q15125 | 2/20 | 0.43 |
| ▸ | DHCR7 | Q9UBM7 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242981 | 1.00 | CYP17A1 (0.50) | CYP17A1ACHEBCHEEBPDHCR7 | |
| SCHEMBL11243490 | 0.86 | SRD5A2 (0.59) | ACHEBCHEEBPDHCR7SRD5A2 | |
| SCHEMBL11243498 | 0.86 | SRD5A2 (0.59) | ACHEBCHEEBPDHCR7SRD5A2 | |
| SCHEMBL11235256 | 0.82 | CYP19A1 (0.51) | SRD5A2GPBAR1SRD5A1 | |
| SCHEMBL11235253 | 0.82 | CYP19A1 (0.51) | SRD5A2GPBAR1SRD5A1 | |
| SCHEMBL11239863 | 0.80 | SRD5A1 (0.43) | ACHESRD5A2GPBAR1SRD5A1 | |
| SCHEMBL11239844 | 0.80 | SRD5A1 (0.43) | ACHESRD5A2GPBAR1SRD5A1 | |
| SCHEMBL11257890 | 0.79 | HSD17B3 (0.53) | GPBAR1 | |
| SCHEMBL11257889 | 0.79 | HSD17B3 (0.53) | GPBAR1 | |
| SCHEMBL11240580 | 0.79 | SRD5A2 (0.43) | ACHEBCHEEBPDHCR7SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317817-A | SKIN DISORDERS; ACEME; ENZYME INHIBITORS | RICHARDSON-MERRELL INC. (US) | 1982-03-02 | — | — | US | disclosed |