Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 6/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239863 | 1.00 | SRD5A1 (0.43) | SRD5A1SRD5A2ARPTPN2PTPN1 | |
| SCHEMBL11235253 | 0.86 | CYP19A1 (0.51) | SRD5A1SRD5A2ARGPBAR1 | |
| SCHEMBL11235256 | 0.86 | CYP19A1 (0.51) | SRD5A1SRD5A2ARGPBAR1 | |
| SCHEMBL11243498 | 0.84 | SRD5A2 (0.59) | SRD5A1SRD5A2AKR1B10AKR1B1GPBAR1 | |
| SCHEMBL11243490 | 0.84 | SRD5A2 (0.59) | SRD5A1SRD5A2AKR1B10AKR1B1GPBAR1 | |
| SCHEMBL11257890 | 0.83 | HSD17B3 (0.53) | AKR1B10AKR1B1GPBAR1 | |
| SCHEMBL11257889 | 0.83 | HSD17B3 (0.53) | AKR1B10AKR1B1GPBAR1 | |
| SCHEMBL11242975 | 0.80 | CYP17A1 (0.50) | SRD5A1SRD5A2GPBAR1ACHE | |
| SCHEMBL11242981 | 0.80 | CYP17A1 (0.50) | SRD5A1SRD5A2GPBAR1ACHE | |
| SCHEMBL11253127 | 0.77 | SRD5A1 (0.39) | SRD5A1SRD5A2ARPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317817-A | SKIN DISORDERS; ACEME; ENZYME INHIBITORS | RICHARDSON-MERRELL INC. (US) | 1982-03-02 | — | — | US | disclosed |