Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL956111 | 0.88 | KCNA3 (0.49) | KCNA3CCR3SIGMAR1ACHEDRD2 | |
| SCHEMBL956109 | 0.88 | KCNA3 (0.49) | KCNA3CCR3SIGMAR1ACHEDRD2 | |
| Hydrochloric Acid SCHEMBL954583 | 0.87 | KCNA3 (0.48) | KCNA3CCR3SIGMAR1ACHEDRD2 | |
| Hydrochloric Acid SCHEMBL954585 | 0.87 | KCNA3 (0.48) | KCNA3CCR3SIGMAR1ACHEDRD2 | |
| SCHEMBL4186493 | 0.85 | KCNA3 (0.55) | KCNA3CCR3SIGMAR1ACHEDRD2 | |
| SCHEMBL11225253 | 0.85 | SLC6A3 (0.44) | KCNA3CCR3SIGMAR1ACHEGBA1 | |
| Hydrochloric Acid SCHEMBL10360726 | 0.84 | KCNA3 (0.53) | KCNA3CCR3SIGMAR1ACHEDRD2 | |
| SCHEMBL11226666 | 0.83 | KCNA3 (0.40) | KCNA3OPRM1DRD2DRD3 | |
| SCHEMBL11223736 | 0.80 | KCNA3 (0.42) | KCNA3SIGMAR1OPRM1DRD2DRD3 | |
| SCHEMBL11234010 | 0.79 | CYP3A4 (0.39) | KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324791-A | DERIVATIVES OF 3,3-DIPHENYL-2-PYRROLIDINONES | A. H. ROBINS COMPANY, INC. (US) | 1982-04-13 | — | — | US | disclosed |
| US-4296037-A | 4,5-Dihydro-3,3-diphenyl-4-hydrocarbylaminomethylfuran-2(3H) ones | A. H. ROBINS COMPANY, INCORPORATED (US) | 1981-10-20 | — | — | US | disclosed |
| US-4144245-A | 4-Hydroxymethyl-2-pyrrolidinones | A. H. ROBINS COMPANY, INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4120969-A | ANALGETIC, ANTIDIARRHEAL ACTIVITY | A. H. ROBINS COMPANY, INCORPORATED (US) | 1978-10-17 | — | — | US | disclosed |
| US-4119637-A | 4-Hydroxymethyl-2-pyrrolidinones | A. H. ROBINS COMPANY, INC. (US) | 1978-10-10 | — | — | US | disclosed |