SCHEMBL11235339

SCHEMBL11235339

CCN(CC)C(=O)c1cc(O)nc(O)c1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.56
RECQL P46063 1/20 0.56
HPGD P15428 8/20 0.51
HSP90AA1 P07900 5/20 0.51
HSP90AB1 P08238 5/20 0.51
ALDH1A1 P00352 5/20 0.51
TDP1 Q9NUW8 1/20 0.49
CYP1A2 P05177 1/20 0.47
BLM P54132 1/20 0.47
MAPT P10636 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MLYCD O95822 1/20 0.44
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6001785 0.79 LMNA (0.59) LMNARECQLHPGDHSP90AA1HSP90AB1
SCHEMBL17264206 0.76 LMNA (0.61) LMNARECQLHPGDHSP90AA1HSP90AB1
SCHEMBL3741746 0.75 HPGD (0.67) LMNARECQLHPGDHSP90AA1HSP90AB1
SCHEMBL9065150 0.74 LMNA (0.59) LMNARECQLHPGDHSP90AA1HSP90AB1
SCHEMBL11782473 0.73 HSP90AA1 (0.56) LMNARECQLHPGDHSP90AA1HSP90AB1
SCHEMBL29175215 0.73 MLYCD (0.55) LMNARECQLHPGDHSP90AA1HSP90AB1
SCHEMBL9581244 0.73 LMNA (0.53) LMNARECQLHPGDHSP90AA1HSP90AB1
SCHEMBL317446 0.73 LMNA (0.53) LMNARECQLHPGDHSP90AA1HSP90AB1
SCHEMBL9188069 0.73 HSP90AA1 (0.62) LMNAHPGDHSP90AA1HSP90AB1ALDH1A1
SCHEMBL5703500 0.73 HPGD (0.73) LMNAHPGDHSP90AA1HSP90AB1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4327018-A Azo dyes and the production and use thereof CIBA-GEIGY CORPORATION (US) 1982-04-27 US disclosed
US-4299764-A Azo reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1981-11-10 US disclosed
US-4294916-A METHINE DYES CIBA-GEIGY AG (CH) 1981-10-13 US disclosed
US-4294917-A METHINE DYES CIBA-GEIGY AG (CH) 1981-10-13 US disclosed
US-4233399-A Photographic elements containing amino-substituted hydroxy-pyridones CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-11-11 US disclosed
US-4182886-A OPTICAL FILTERS IN COLOR PHOTOGRAPHY CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-01-08 US disclosed
US-4160643-A FOR POLYMERS OF ACRYLONITRILE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-07-10 US disclosed
US-4079052-A Diazopigments containing pyridine derivatives CIBA-GEIGY CORPORATION (US) 1978-03-14 US disclosed