Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609000 | 0.85 | ALDH1A1 (0.35) | ALDH1A1SOAT1 | |
| SCHEMBL28655911 | 0.83 | ALDH1A1 (0.48) | ALDH1A1SOAT1LMNAHSD17B10GAA | |
| SCHEMBL21343092 | 0.83 | HCAR2 (0.35) | ALDH1A1SOAT1LMNASMN1; SMN2HCAR2 | |
| SCHEMBL575161 | 0.81 | — | — | |
| SCHEMBL10919035 | 0.81 | — | — | |
| SCHEMBL11144447 | 0.81 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL11251165 | 0.79 | ALDH1A1 (0.30) | ALDH1A1TRPA1 | |
| SCHEMBL38665267 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2HPGDHCAR2 | |
| SCHEMBL9354654 | 0.79 | — | — | |
| SCHEMBL644043 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478391-B | Ornidazole ester prodrug, pharmaceutical composition, and preparation method and application thereof | 南京锐志生物医药有限公司 | 2023-09-15 | — | — | CN | claimed |
| US-4332729-A | CATALYZED CYCLIZATION | THE DOW CHEMICAL COMPANY (US) | 1982-06-01 | — | — | US | claimed |
| CN-113831342-B | Ketorolac derivative, pharmaceutical composition, and preparation method and application thereof | 南京海融医药科技股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| EP-3587403-B1 | N-SUBSTITUTED IMIDAZOLE CARBOXYLATE COMPOUND, PREPARATION METHOD AND USE | WEST CHINA HOSPITAL SICHUAN UNIV (CN) | 2023-08-23 | — | — | EP | disclosed |
| US-20230134672-A1 | KETOROLACO DERIVATIVE, PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF | NANJING HERON PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2023-05-04 | — | — | US | disclosed |
| US-20230134672-A1 | KETOROLACO DERIVATIVE, PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF | NANJING HERON PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2023-05-04 | — | — | US | disclosed |
| US-20230134672-A1 | KETOROLACO DERIVATIVE, PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF | NANJING HERON PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2023-05-04 | — | — | US | disclosed |
| US-20230126556-A1 | IBUPROFEN ESTER DERIVATIVE AND EMULSION PREPARATION THEREOF | NANJING HERON PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2023-04-27 | — | — | US | disclosed |
| US-20230126556-A1 | IBUPROFEN ESTER DERIVATIVE AND EMULSION PREPARATION THEREOF | NANJING HERON PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2023-04-27 | — | — | US | disclosed |
| US-20230000812-A1 | IBUPROFEN ESTER PRODRUG, PHARMACEUTICAL COMPOSITION, PREPARATION METHOD AND APPLICATION | NANJING HERON PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2023-01-05 | — | — | US | disclosed |
| US-20220274911-A1 | ARYLPROPIONIC ACID DERIVATIVE, PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD AND APPLICATION THEREOF | NANJING HERON PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2022-09-01 | — | — | US | disclosed |
| CN-113831342-A | Ketorolac derivative, pharmaceutical composition, preparation method and application thereof | 南京海融医药科技股份有限公司 | 2021-12-24 | — | — | CN | disclosed |
| CN-107652239-B | N-substituted imidazole carboxylic ester compound, preparation method and application | 四川大学华西医院 | 2020-08-04 | — | — | CN | disclosed |
| US-20200231546-A1 | N-SUBSTITUTED IMIDAZOLE CARBOXYLATE COMPOUND, PREPARATION METHOD AND USE | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2020-07-23 | — | — | US | disclosed |
| EP-2755983-A1 | SUBSTITUTED CARBONYLOXYMETHYLPHOSPHORAMIDATE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS | IDENIX Pharmaceuticals, Inc. (US) | 2014-07-23 | — | — | EP | disclosed |
| WO-2013039920-A1 | SUBSTITUTED CARBONYLOXYMETHYLPHOSPHORAMIDATE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS | IDENIX PHARMACEUTICALS, INC. (US) | 2013-03-21 | — | — | WO | disclosed |
| EP-0060904-A1 | A process for making vicinal epoxides and alkyl halides or alkylene dihalides from carbonate esters | THE DOW CHEMICAL COMPANY (US) | 1982-09-29 | — | — | EP | disclosed |
| US-4332729-A | CATALYZED CYCLIZATION | THE DOW CHEMICAL COMPANY (US) | 1982-06-01 | — | — | US | disclosed |
| US-4331604-A | Preparation of cyclic carbonates | THE DOW CHEMICAL COMPANY (US) | 1982-05-25 | — | — | US | disclosed |
| US-4261906-A | DECOMPOSITION OF BETA-HALOALKYL CARBONATE IN PRESENCE OF QUATERNARY AMMONIUM OR PHOSPHONIUM SALT | THE DOW CHEMICAL COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000812-A1 | IBUPROFEN ESTER PRODRUG, PHARMACEUTICAL COMPOSITION, PREPARATION METHOD AND APPLICATION | PTGER1, CYP4A11, FABP4 | ALDH1A1 851/4885SOAT1 1539/4885LMNA 2133/4885 |
| US-20230134672-A1 | KETOROLACO DERIVATIVE, PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP51A1, CYP4A11, CYP4F11 | ALDH1A1 155/4885SOAT1 325/4885LMNA 2135/4885 |
| US-20230126556-A1 | IBUPROFEN ESTER DERIVATIVE AND EMULSION PREPARATION THEREOF | CYP2C9, CYP2C19, CYP4B1 | ALDH1A1 828/4885SOAT1 2001/4885LMNA 3272/4885 |
| US-20200231546-A1 | N-SUBSTITUTED IMIDAZOLE CARBOXYLATE COMPOUND, PREPARATION METHOD AND USE | CHRM1, CYP2C18, CYP2E1 | ALDH1A1 1425/4885SOAT1 2543/4885LMNA 1556/4885 |
| US-20220274911-A1 | ARYLPROPIONIC ACID DERIVATIVE, PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD AND APPLICATION THEREOF | CYP2A7, CYP2A6, CYP3A7 | ALDH1A1 43/4885SOAT1 2322/4885LMNA 1498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.