Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | BRD1 | O95696 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12725548 | 0.85 | SLC6A4 (0.57) | SLC6A4HTR2ATRIM24BRD1BRPF1 | |
| SCHEMBL3755350 | 0.82 | ALDH1A1 (0.53) | SLC6A4LMNAL3MBTL1ALDH1A1TSHR | |
| SCHEMBL30695769 | 0.80 | TSHR (0.50) | BRD4ALDH1A1LTA4HTSHRHTT | |
| SCHEMBL424805 | 0.80 | LTA4H (0.50) | SLC6A4HTR2AL3MBTL1ALDH1A1LTA4H | |
| SCHEMBL822665 | 0.80 | TSHR (0.50) | BRD4ALDH1A1LTA4HTSHRHTT | |
| SCHEMBL11604036 | 0.80 | RXRA (0.56) | PPARG | |
| SCHEMBL13680419 | 0.79 | SLC6A4 (0.50) | SLC6A4HTR2AKCNH2ALDH1A1TSHR | |
| SCHEMBL232763 | 0.79 | SMN1; SMN2 (0.56) | SLC6A4BRD4LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL22199172 | 0.78 | SLC6A4 (0.42) | SLC6A4HTR2ATRIM24BRD1BRPF1 | |
| SCHEMBL11602645 | 0.78 | CYP1A2 (0.48) | SLC6A4HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141439-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-09 | — | — | WO | disclosed |
| US-4331821-A | ULTRAVIOLET RADIATION OF A VAPORIZED ALKYLBENZEN AND HALOGEN GAS MIXTURE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-25 | — | — | US | disclosed |
| US-4231953-A | Fluoro substituted aryl esters and thiolesters of amino acids | ZOECON CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| US-4229368-A | Esters and thiolesters of unsaturated acids | ZOECON CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4225533-A | Fluorobenzyl esters of cyclopropanecarboxylic acids | ZOECON CORPORATION (US) | 1980-09-30 | — | — | US | disclosed |