Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.45 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11239641 | 0.99 | HTT (0.47) | HTTGUCY1A1GUCY1B1KMT2AMEN1 | |
| SCHEMBL11241668 | 0.86 | HDAC6 (0.40) | HTTKMT2AMEN1GAAHDAC6 | |
| Hydrochloric Acid SCHEMBL11248320 | 0.85 | HDAC6 (0.39) | HTTKMT2AMEN1GAAHDAC6 | |
| SCHEMBL11244735 | 0.80 | TSHR (0.36) | KMT2AGAASMN1; SMN2LMNAALOX12 | |
| Hydrochloric Acid SCHEMBL11237752 | 0.79 | TSHR (0.36) | KMT2AGAASMN1; SMN2LMNAALOX12 | |
| SCHEMBL11229508 | 0.78 | THRB (0.42) | HTTKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL11235538 | 0.78 | HTT (0.47) | HTTGUCY1A1GUCY1B1KMT2AMEN1 | |
| SCHEMBL11231203 | 0.78 | NPC1 (0.38) | HTTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11238357 | 0.77 | NPC1 (0.43) | HTTKMT2AMEN1GAAHDAC8 | |
| Hydrochloric Acid SCHEMBL11238437 | 0.77 | THRB (0.41) | HTTKMT2AMEN1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |