Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11237752 | 0.99 | TSHR (0.36) | TSHRHSD17B10SLC6A4MAPK1SMN1; SMN2 | |
| SCHEMBL11239338 | 0.84 | DRD3 (0.33) | SLC6A4MAPK1PPARGPPARADRD2 | |
| Hydrochloric Acid SCHEMBL11235609 | 0.83 | DRD3 (0.33) | SLC6A4MAPK1PPARGPPARADRD2 | |
| Hydrochloric Acid SCHEMBL11230532 | 0.81 | MAPT (0.46) | SLC6A4SMN1; SMN2PPARGPPARA | |
| SCHEMBL11235563 | 0.80 | HTT (0.48) | SMN1; SMN2ALOX12GAALMNAKMT2A | |
| SCHEMBL11242830 | 0.80 | TRPV4 (0.35) | SLC6A4PPARGPPARADRD2DRD4 | |
| SCHEMBL11243710 | 0.79 | HPGD (0.53) | TSHRSMN1; SMN2CHRM1KMT2A | |
| SCHEMBL11229508 | 0.79 | THRB (0.42) | CYP1A2CYP3A4HTR2AALOX12LMNA | |
| Hydrochloric Acid SCHEMBL11239641 | 0.79 | HTT (0.47) | SMN1; SMN2ALOX12GAALMNAKMT2A | |
| Hydrochloric Acid SCHEMBL11238437 | 0.78 | THRB (0.41) | CYP1A2CYP3A4HTR2AALOX12LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |