Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11238437 | 0.99 | THRB (0.41) | THRBALDH1A1ALPLALPIALOX12 | |
| SCHEMBL11231203 | 0.89 | NPC1 (0.38) | ALDH1A1ALOX12KMT2ALMNAMAPT | |
| Hydrochloric Acid SCHEMBL11226921 | 0.88 | RAB9A (0.37) | THRBALDH1A1ALOX12KDM4EKMT2A | |
| SCHEMBL11239338 | 0.84 | DRD3 (0.33) | ALDH1A1TAAR1MAPTHTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL11235609 | 0.83 | DRD3 (0.33) | ALDH1A1TAAR1MAPTHTR1AHTR2A | |
| SCHEMBL11238357 | 0.81 | NPC1 (0.43) | ALDH1A1ALOX12KDM4ENPSR1KMT2A | |
| Hydrochloric Acid SCHEMBL11233901 | 0.80 | NPC1 (0.43) | ALDH1A1ALOX12KDM4ENPSR1KMT2A | |
| SCHEMBL11244735 | 0.79 | TSHR (0.36) | ALOX12KMT2ALMNACYP1A2CYP3A4 | |
| SCHEMBL11229502 | 0.78 | THRB (0.46) | THRBALDH1A1ALPLALPIALOX12 | |
| Hydrochloric Acid SCHEMBL11237752 | 0.78 | TSHR (0.36) | ALOX12KMT2ALMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |