Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.51 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123260 | 0.97 | FFAR1 (0.60) | FFAR1KMT2AFFAR4NR4A2PTGES | |
| SCHEMBL1122963 | 0.96 | FFAR1 (0.65) | FFAR1KMT2AFFAR4PTGESSMN1; SMN2 | |
| SCHEMBL1122984 | 0.94 | NR4A2 (0.56) | FFAR1KMT2ANR4A2PTGESSMPD1 | |
| SCHEMBL1123113 | 0.92 | FFAR1 (0.62) | FFAR1FFAR4NR4A2PTGESSMN1; SMN2 | |
| SCHEMBL1122854 | 0.91 | FFAR1 (0.60) | FFAR1FFAR4NR4A2PTGESSMPD1 | |
| SCHEMBL1123394 | 0.91 | KMT2A (0.52) | FFAR1KMT2AFFAR4NR4A2PTGES | |
| SCHEMBL1123468 | 0.89 | KMT2A (0.54) | FFAR1KMT2ANR4A2PTGESSMPD1 | |
| SCHEMBL1123118 | 0.89 | KMT2A (0.58) | FFAR1KMT2AFFAR4NR4A2PTGES | |
| SCHEMBL1123421 | 0.88 | NPC1 (0.53) | FFAR1KMT2ANR4A2PTGESMAOB | |
| SCHEMBL1123557 | 0.88 | PTGES (0.52) | FFAR1KMT2ANR4A2PTGESSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |