Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123557 | 0.95 | PTGES (0.52) | KMT2AFFAR1NR4A2SMPD1MAOB | |
| SCHEMBL1122949 | 0.93 | FFAR1 (0.52) | FFAR1MAOBPTGESPPARGPPARA | |
| SCHEMBL1123559 | 0.91 | FFAR1 (0.62) | KMT2AFFAR1NR4A2SMPD1MAOB | |
| SCHEMBL1123395 | 0.90 | F10 (0.51) | KMT2ANR4A2SMPD1PTGESF10 | |
| SCHEMBL1123260 | 0.90 | FFAR1 (0.60) | KMT2AFFAR1NR4A2SMPD1MAOB | |
| SCHEMBL1123247 | 0.89 | SLC2A1 (0.47) | KMT2ASMPD1MAOBF10PPARG | |
| SCHEMBL1122385 | 0.88 | PPARG (0.47) | KMT2AF10PPARGPPARA | |
| SCHEMBL1122912 | 0.87 | LPAR1 (0.49) | KMT2AFFAR1L3MBTL1PTGESF10 | |
| SCHEMBL1123593 | 0.87 | NR4A1 (0.48) | KMT2ANR4A2F10PPARG | |
| SCHEMBL1122963 | 0.87 | FFAR1 (0.65) | KMT2AFFAR1PTGESFFAR4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| CN-1835914-A | New benzamides as PPAR[upsilon] modulators | S A L V A T LAB SA (ES) | 2006-09-20 | — | — | CN | disclosed |
| EP-1644321-A2 | NEW BENZAMIDES AS PPATY MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110983-A2 | NEW BENZAMIDES AS PPARϒ MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-12-23 | — | — | WO | disclosed |