SCHEMBL11235652

SCHEMBL11235652

COCc1c(Cl)c(Cl)c(COC)c(Cl)c1Cl

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
KMT2A Q03164 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
IGF1R P08069 1/20 0.31
SRC P12931 1/20 0.31
AXL P30530 1/20 0.31
PTK2 Q05397 1/20 0.31
AURKB Q96GD4 1/20 0.31
ALK Q9UM73 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6442145 0.87 GCGR (0.33) IGF1RSRCAXLPTK2AURKB
SCHEMBL12016023 0.73 CYP2D6 (0.36)
SCHEMBL2094314 0.73 POLB (0.30)
SCHEMBL580105 0.73 KDM4E (0.38) KDM4EMEN1GAAMAPTCACNA1B
SCHEMBL28781573 0.70
SCHEMBL2095745 0.69 ALDH1A1 (0.39) MEN1MAPTKMT2A
SCHEMBL4796836 0.69 SMN1; SMN2 (0.48) KDM4EKMT2A
SCHEMBL9685153 0.69 IGF1R (0.41) KDM4EMEN1GAAMAPTCACNA1B
SCHEMBL12016011 0.68 BDKRB2 (0.41) KDM4E
SCHEMBL12016033 0.68 MAPT (0.36) KDM4EMEN1GAAMAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7718343-B2 Decomposable resin composition and pattern-forming material including the same FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20080070154-A1 DECOMPOSABLE RESIN COMPOSITION AND PATTERN-FORMING MATERIAL INCLUDING THE SAME FUJIFILM CORPORATION (JP) 2008-03-20 US disclosed
US-4318821-A Polymeric compositions ALBRIGHT & WILSON LIMITED (GB) 1982-03-09 US disclosed
US-4020035-A PHENOLIC ALBRIGHT & WILSON LIMITED (EN) 1977-04-26 US disclosed