SCHEMBL11235784

SCHEMBL11235784

NCCNCc1ccccc1Br

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.55
POLB P06746 1/20 0.48
CA12 O43570 5/20 0.46
CA2 P00918 5/20 0.46
CA9 Q16790 4/20 0.46
KDM4E B2RXH2 1/20 0.46
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CHRM2 P08172 3/20 0.45
MC4R P32245 1/20 0.44
MC5R P33032 1/20 0.44
IDO1 P14902 2/20 0.44
MC1R Q01726 1/20 0.42
MPO P05164 3/20 0.42
SLC6A4 P31645 1/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18575559 0.85 CA12 (0.54) CA12CA2CA9KDM4ETSHR
SCHEMBL28645729 0.82 TAAR1 (0.64) TAAR1POLBCA12CA9CHRM2
SCHEMBL4716056 0.81 CA12 (0.52) TAAR1POLBCA12CA2CA9
SCHEMBL16619192 0.80 ALDH1A1 (0.51) TAAR1POLBCA12CA2CA9
SCHEMBL21674165 0.80 TAAR1 (0.50) TAAR1POLBCA12CA2CA9
SCHEMBL30192689 0.79 CA12 (0.48) CA12CA2CA9KDM4ETSHR
SCHEMBL17400756 0.78 CA12 (0.56) CA12CA2CA9KDM4ETSHR
SCHEMBL4706607 0.78 CHRM2 (0.71) TAAR1CA12CA2CA9KDM4E
SCHEMBL7245746 0.78 MPO (0.62) TAAR1CA12CA2CA9MPO
SCHEMBL5547862 0.76 CA12 (0.46) CA12CA2CA9KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4315846-A FUNGICIDES TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1982-02-16 US disclosed
EP-0037861-A1 Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1981-10-21 EP disclosed