Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | MC5R | P33032 | 1/20 | 0.44 |
| ▸ | MC1R | Q01726 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18575559 | 0.89 | CA12 (0.54) | CA12CA2CA9KDM4ETSHR | |
| SCHEMBL30192689 | 0.83 | CA12 (0.48) | CA12CA2CA9KDM4ETSHR | |
| SCHEMBL7245746 | 0.78 | MPO (0.62) | CA12CA2CA9MPOSLC6A4 | |
| SCHEMBL4706607 | 0.78 | CHRM2 (0.71) | CA12CA2CA9KDM4ETSHR | |
| SCHEMBL5191623 | 0.76 | MC1R (0.54) | CA12CA2CA9KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL4707535 | 0.76 | CHRM2 (0.69) | CA12CA2CA9KDM4ETSHR | |
| SCHEMBL11235784 | 0.76 | TAAR1 (0.55) | CA12CA2CA9KDM4ETSHR | |
| SCHEMBL2549012 | 0.76 | CA12 (0.78) | CA12CA2CA9KDM4ETSHR | |
| SCHEMBL4917141 | 0.76 | CHRM2 (0.72) | CA12CA2CA9KDM4ETSHR | |
| SCHEMBL11239485 | 0.76 | TAAR1 (0.55) | CA12CA2CA9KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4135683-A1 | THERAPEUTIC USE OF PLEUROMUTILINS | Nabriva Therapeutics GMBH (AT) | 2023-02-22 | — | — | EP | claimed |
| WO-2021209596-A1 | THERAPEUTIC USE OF PLEUROMUTILINS | Nabriva Therapeutics GmbH (AT) | 2021-10-21 | — | — | WO | claimed |
| US-9701628-B2 | 12-epi pleuromutilins | NABRIVA THERAPEUTICS AG (AT) | 2017-07-11 | — | — | US | claimed |
| US-20160332963-A1 | 12-EPI PLEUROMUTILINS | Nabriva Therapeutics GmbH (AT) | 2016-11-17 | — | — | US | claimed |
| US-20070092776-A1 | Sulfonic acid group-containing organic-silica composite membrane and method for producing thereof | EBARA CORPORATION (JP) | 2007-04-26 | — | — | US | claimed |
| WO-2005049183-A1 | SULFONIC ACID GROUP-CONTAINING ORGANIC-SILICA COMPOSITE MEMBRANE AND METHOD FOR PRODUCING THEREOF | EBARA CORPORATION (JP) | 2005-06-02 | — | — | WO | claimed |
| CN-117500809-A | Novel 12-epimeric-mollin compounds and uses thereof | 纳布里瓦治疗有限责任公司 | 2024-02-02 | — | — | CN | disclosed |
| EP-3491096-B1 | GEL-TYPE THERMAL INTERFACE MATERIAL | HONEYWELL INT INC (US) | 2021-06-16 | — | — | EP | disclosed |
| EP-3491096-A2 | GEL-TYPE THERMAL INTERFACE MATERIAL | Honeywell International Inc. (US) | 2019-06-05 | — | — | EP | disclosed |
| WO-2018022288-A2 | GEL-TYPE THERMAL INTERFACE MATERIAL | HONEYWELL INTERNATIONAL INC. (US) | 2018-02-01 | — | — | WO | disclosed |
| US-20180030328-A1 | GEL-TYPE THERMAL INTERFACE MATERIAL | HONEYWELL INTERNATIONAL INC. | 2018-02-01 | — | — | US | disclosed |
| US-20070092776-A1 | Sulfonic acid group-containing organic-silica composite membrane and method for producing thereof | EBARA CORPORATION (JP) | 2007-04-26 | — | — | US | disclosed |
| WO-2005049183-A1 | SULFONIC ACID GROUP-CONTAINING ORGANIC-SILICA COMPOSITE MEMBRANE AND METHOD FOR PRODUCING THEREOF | EBARA CORPORATION (JP) | 2005-06-02 | — | — | WO | disclosed |
| EP-0537744-A1 | Novel organosilicon compound | Shin-Etsu Chemical Co., Ltd. (JP) | 1993-04-21 | — | — | EP | disclosed |
| US-4863831-A | Photosensitive lithographic plate requiring no dampening water having a gelatin primer layer | FUJI PHOTO FILM CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| US-4861698-A | HARDENED GELATIN, SILICONE RUBBER | FUJI PHOTO FILM CO., LTD. (JP) | 1989-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160332963-A1 | 12-EPI PLEUROMUTILINS | MLN, TCF12, PLEC | CA12 655/4885CA2 4318/4885CA9 1168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.