Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990800 | 0.85 | TDP1 (0.57) | CARM1PRMT6TDP1DRD2DRD4 | |
| SCHEMBL11385381 | 0.84 | PARP10 (0.50) | PARP15PARP10PARP2 | |
| SCHEMBL9283085 | 0.83 | DRD4 (0.45) | DRD2DRD4PARP15PARP10PARP2 | |
| SCHEMBL9283087 | 0.83 | DRD4 (0.45) | DRD2DRD4PARP15PARP10PARP2 | |
| SCHEMBL7733010 | 0.82 | SIGMAR1 (0.58) | TDP1PARP15PARP10PARP2 | |
| SCHEMBL11059880 | 0.82 | SIGMAR1 (0.58) | TDP1PARP15PARP10PARP2 | |
| SCHEMBL19985635 | 0.80 | PARP15 (0.41) | TDP1PARP15PARP10PARP2 | |
| SCHEMBL11404908 | 0.79 | SIGMAR1 (0.55) | — | |
| SCHEMBL11234530 | 0.79 | SIGMAR1 (0.55) | TDP1PARP15PARP10PARP2 | |
| SCHEMBL8731137 | 0.79 | TDP1 (0.42) | TDP1PARP15PARP10PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57031645-A | — | — | None | — | — | JP | disclosed |
| JP-S5731645-A | 4-HALOGENOBENZOIC ACID 4'-(TRANS-4\"-ALKYLCYCLOHEXYL)PHENYL ESTER | CHISSO CORP | 1982-02-20 | — | — | JP | disclosed |