Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9283087 | 1.00 | DRD4 (0.45) | DRD4DRD2PARP15PARP10PARP2 | |
| SCHEMBL24180195 | 0.86 | PARP15 (0.55) | DRD4DRD2PARP15PARP10PARP2 | |
| SCHEMBL11235792 | 0.83 | CARM1 (0.46) | DRD4DRD2PARP15PARP10PARP2 | |
| SCHEMBL7733010 | 0.83 | SIGMAR1 (0.58) | PARP15PARP10PARP2SIGMAR1 | |
| SCHEMBL11059880 | 0.83 | SIGMAR1 (0.58) | PARP15PARP10PARP2SIGMAR1 | |
| SCHEMBL9256603 | 0.81 | DRD4 (0.41) | DRD4DRD2PARP15PARP10PARP2 | |
| SCHEMBL9256596 | 0.81 | DRD4 (0.41) | DRD4DRD2PARP15PARP10PARP2 | |
| SCHEMBL9256583 | 0.81 | DRD4 (0.41) | DRD4DRD2PARP15PARP10PARP2 | |
| SCHEMBL19985635 | 0.80 | PARP15 (0.41) | PARP15PARP10PARP2SIGMAR1 | |
| SCHEMBL11234530 | 0.79 | SIGMAR1 (0.55) | PARP15PARP10PARP2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423520-B1 | Liquid crystalline composition for the use in a twisted nematic cell | MERCK PATENT GMBH (DE) | 1995-08-02 | — | — | EP | disclosed |