Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059880 | 1.00 | SIGMAR1 (0.58) | SIGMAR1SLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL11234530 | 0.96 | SIGMAR1 (0.55) | SIGMAR1SLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL11404908 | 0.96 | SIGMAR1 (0.55) | SIGMAR1SLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL20766385 | 0.87 | SIGMAR1 (0.73) | SIGMAR1SLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL9283087 | 0.83 | DRD4 (0.45) | SIGMAR1PARP15PARP10PARP2 | |
| SCHEMBL9283085 | 0.83 | DRD4 (0.45) | SIGMAR1PARP15PARP10PARP2 | |
| SCHEMBL11235792 | 0.82 | CARM1 (0.46) | PARP15PARP10PARP2TDP1 | |
| SCHEMBL25727760 | 0.80 | SIGMAR1 (0.64) | SIGMAR1SLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL2352622 | 0.79 | GRIA1 (0.41) | SIGMAR1KCNH2KDM1AEGLN2 | |
| SCHEMBL7751867 | 0.79 | GRIA1 (0.41) | SIGMAR1KCNH2KDM1AEGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59080485-A | — | — | None | — | — | JP | disclosed |
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| US-5858270-A | Difluorooxymethane derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |
| JP-S5980485-A | LIQUID CRYSTAL COMPOSITION | SHARP CORP | 1984-05-09 | — | — | JP | disclosed |