SCHEMBL11235922

SCHEMBL11235922

c1ccc(-c2ccc3nc[nH]c3c2)nc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 8/20 0.58
QPCTL Q9NXS2 6/20 0.58
TGFBR1 P36897 1/20 0.57
TGFBR2 P37173 1/20 0.57
KDM4E B2RXH2 3/20 0.52
ALDH1A1 P00352 2/20 0.52
HPGD P15428 2/20 0.52
RAB9A P51151 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
NPC1 O15118 1/20 0.52
TP53 P04637 1/20 0.52
HTT P42858 1/20 0.50
ALOX5AP P20292 1/20 0.49
FEN1 P39748 1/20 0.49
PRKCI P41743 2/20 0.49
PIK3CD O00329 1/20 0.48
PIK3CA P42336 1/20 0.48
PI4KA P42356 1/20 0.48
PIK3CG P48736 1/20 0.48
PI4KB Q9UBF8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11235894 0.86 TGFBR1 (0.45) QPCTQPCTLTGFBR1TGFBR2KDM4E
SCHEMBL8634290 0.81 QPCT (0.68) QPCTQPCTLKDM4EALDH1A1HPGD
SCHEMBL2462345 0.80 QPCT (0.68) QPCTQPCTLKDM4EALDH1A1HPGD
Dipyridyl SCHEMBL28296592 0.80 KDM4E (0.54) TGFBR1TGFBR2KDM4EALDH1A1HPGD
SCHEMBL11783195 0.80 QPCT (0.59) QPCTQPCTLTGFBR1TGFBR2KDM4E
SCHEMBL15639725 0.78 QPCT (0.60) QPCTQPCTLKDM4EALDH1A1HPGD
SCHEMBL22418756 0.77 QPCT (0.64) QPCTQPCTLKDM4EALDH1A1HPGD
SCHEMBL28190281 0.77 QPCT (0.64) QPCTQPCTLKDM4EALDH1A1HPGD
SCHEMBL29776592 0.77 PIK3CD (0.42) TGFBR1TGFBR2KDM4EHPGDRAB9A
SCHEMBL28443390 0.77 ALOX5AP (0.48) QPCTQPCTLTGFBR1TGFBR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107422-A1 6-(PYRIDIN-4-YL)-1H-BENZO[D]IMIDAZOLE DERIVATIVES AS CAMK2 INHIBITORS FOR THE TREATMENT OF HEART FAILURE BRISTOL-MYERS SQUIBB COMPANY (US) 2026-05-21 WO disclosed
EP-0055453-A3 5-(PYRIDINYL)-BENZIMIDAZOLE DERIVATIVES AND PREPARATION STERLING DRUG INC. (US) 1982-09-01 EP disclosed
EP-0055453-A2 5-(Pyridinyl)-benzimidazole derivatives and preparation STERLING DRUG INC. (US) 1982-07-07 EP disclosed
EP-0055453-A2 5-(Pyridinyl)-benzimidazole derivatives and preparation STERLING DRUG INC. (US) 1982-07-07 EP disclosed