Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252785 | 0.91 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AHPGDTP53 | |
| SCHEMBL11231758 | 0.85 | TSHR (0.44) | SMN1; SMN2HPGDALDH1A1HTTGAA | |
| SCHEMBL11245560 | 0.82 | CYP3A4 (0.41) | SMN1; SMN2ALDH1A1LMNAGAASLC6A2 | |
| SCHEMBL11246880 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2TP53ALDH1A1MAPTHTT | |
| SCHEMBL11233129 | 0.80 | TSHR (0.41) | SMN1; SMN2HPGDALDH1A1HTTGAA | |
| SCHEMBL11244188 | 0.79 | RAB9A (0.52) | SMN1; SMN2NPC1RAB9AHPGDCYP11B2 | |
| SCHEMBL11235465 | 0.77 | GAA (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL7143404 | 0.75 | CYP11B2 (0.50) | SMN1; SMN2NPC1RAB9AHPGDTP53 | |
| SCHEMBL11238290 | 0.75 | CYP3A4 (0.44) | NPC1POLBLMNAGAASLC6A2 | |
| Bromide SCHEMBL6283092 | 0.74 | CYP11B2 (0.49) | SMN1; SMN2NPC1RAB9AHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339455-A | 1-(3-Pyridyl)-2,2,2-trihaloethyl compounds and fungicidal compositions containing the same | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1982-07-13 | — | — | US | disclosed |
| US-4189486-A | FUNGICIDES | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1980-02-19 | — | — | US | disclosed |