Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238689 | 1.00 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2LMNATLR2 | |
| SCHEMBL11235830 | 0.85 | HPGD (0.53) | HDAC1HDAC2HDAC3HDAC8HPGD | |
| SCHEMBL11236735 | 0.85 | HPGD (0.53) | HDAC1HDAC2HDAC3HDAC8HPGD | |
| SCHEMBL11237791 | 0.85 | HPGD (0.53) | HDAC1HDAC2HDAC3HDAC8HPGD | |
| SCHEMBL11236862 | 0.85 | HPGD (0.53) | HDAC1HDAC2HDAC3HDAC8HPGD | |
| SCHEMBL11246827 | 0.83 | HPGD (0.46) | SMN1; SMN2LMNATLR2HPGDMEN1 | |
| SCHEMBL11238170 | 0.81 | FAAH (0.55) | NPC1RAB9ASMN1; SMN2LMNATLR2 | |
| SCHEMBL11244302 | 0.81 | CYP4F2 (0.56) | HPGDMAPTTLR7ALDH1A1 | |
| SCHEMBL11243340 | 0.81 | CYP4F2 (0.56) | HPGDMAPTTLR7ALDH1A1 | |
| SCHEMBL11240733 | 0.81 | CYP4F2 (0.56) | HPGDMAPTTLR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |